The Supp Digest | 2025 Wrapped
Welcome to the final issue of The Digest for 2025. To close out the year, we’re showcasing the top products, nutrients, protocols, and community moments across SuppCo. We’re thrilled with how much our community has grown this year!
2025 Top Products
Since our launch in November 2024, the SuppCo community has grown to over 450,000 supplement users. Here are the top 5 most stacked products across our community this year:
1️⃣ Seed DS-01 Daily Synbiotic
2️⃣ Thorne Creatine
3️⃣ Pure Encapsulations Magnesium Glycinate
5️⃣ Thorne Super EPA
2025 Top Nutrients
When it comes to most stacked nutrients, core vitamins and minerals took the lead this year:
1️⃣ Vitamin D3 led the pack for most popular nutrient across SuppCo users, appearing in 46% of stacks
2️⃣ Magnesium followed in a close second, with over 40% of users having a form of magnesium (glycinate, threonate, citrate, malate) in their stack
3️⃣ Vitamin C was the third most popular nutrient in 2025, with just shy of 40% of users including it in their stack
2025 Top Protocols
In May we launched Expert Protocols to help SuppCo users find targeted advice on supplements for specific health goals. Here are the most followed protocols from our Experts:
1️⃣ Dr. Natalie Crawford’s Women’s Essential Hormone Support protocol, which features vitamin D3, omega-3 fatty acids, magnesium glycinate, fiber, and folic acid.
2️⃣ Dr. Mark Hyman’s Essential Longevity Support protocol, which includes NMN, urolithin A, and ubiquinol among other key longevity nutrients.
3️⃣ Dr. Mark Hyman’s Essential Brain Health protocol, which highlights l-carnitine, phosphatidylserine, and NAC as core cognition nutrients.
2025 Top Community Moments
Across articles, supplement lists, and posts, there are countless ways for our community to interact on the SuppCo app. Here are a few community moments that took off this year:
Most popular article: the SuppCo Tested series was a community favorite across 2025 and the retrospective article on what we learned from testing supplements purchased on Amazon took gold for most popular SuppCo article in 2025.
Most popular community list: over 600 public, user-generated supplements lists were created this year, with the most popular being a handy list for supplements that can help with GLP-1 related hair loss
Most popular community post: last week we launched community posts, a forum where users can post questions or experiences they’ve had related to specific nutrients. So far, the most popular post has been around fish oils and whether they make you nauseous. Give it a read here!
Thank You
Before signing off on this last Digest for 2025, I wanted to personally thank each of you for the support you’ve shown SuppCo this year. SuppCo’s first year has been a wonderful one, and I’ve been so inspired by the thoughtfulness and rigour of this community. I can’t wait to keep building the SuppCo experience for you all in 2026. Cheers and happy holidays!