The Supp Digest | Brain Health By the Numbers
Welcome to The Digest, your guide to key insights and updates across the SuppCo community.
In this series, we dig into the fascinating (and anonymous) trends SuppCo sees from our unique vantage point to help you make sense of supplements.
When it comes to longevity, brain health and mental acuity are often top concerns. In our latest Science Corner, we highlighted 5 promising supplements and one up-and-coming nutrient for nourishing and protecting your brain for the long-term.
In this installment of The Digest, we're diving into the SuppCo user data on these 6 brain-supporting supplements to see how our community is approaching cognitive wellness.
Omega-3 Fatty Acids: The Community Favorite
One of the most popular nutrients across SuppCo users, omega-3 fatty acids show up in 34% of stacks and over 3,200 products in the SuppCo database.
Omega-3 fatty acids are one of the most recommended supplements not only for brain health but across our Expert Protocols, with appearances in Essential Fertility Support, Essential Heart Health, and GLP-1 Core Nutrient Support.
When it comes to choosing omega-3 fatty acids, make sure to opt for products with at least 70% EPA/DHA. Here are a few products that stand out:
TrustScore Pick: Thorne's Super EPA (9.44 Excellent)
Most Popular: Nordic Natural's Omega-3 (8.06 Very Good)
Turmeric Curcumin: The Versatile Powerhouse
Not far behind in popularity, turmeric curcumin is present in 31% of SuppCo stacks and appears in over 8,500 products in our database.
Its benefits also reach beyond the brain. You'll find turmeric curcumin in our Essential Bone & Joint Support and Bloating Support protocols, proving that this golden spice isn't just good for your mind—it's working throughout your body.
When it comes to product selection, you can maximize your brain benefits with products standardized to at least 95% curcuminoids (the bioactive part of turmeric curcumin). SuppCo community consensus when it comes to turmeric curcumin products is strong. The highest TrustScore pick is also the most popular pick: Thorne's Curcumin Phytosome (9.69 Excellent).
CDP-Choline (Citicoline): The Hidden Gem
A far less popular supplement among SuppCo users, CDP-choline shows up in just 1% of stacks and 151 products. CDP-choline flies under the radar, but that doesn't mean it's not worth considering.
If you're curious about products for this more elusive nutrient, we recommend checking out:
TrustScore Pick: SFI Health's CDP Choline 250mg (9.50 Excellent)
Most Popular: Bare Performance Nutrition's Strong Multi-Vitamin (8.94 Very Good) which utilizes CDP-choline as part of a broader multivitamin
Magnesium Threonate: The Targeted Solution
Magnesium products are another heavyweight on the SuppCo platform, with over half of SuppCo users having some form of magnesium in their stack. However, magnesium threonate specifically is a less common entry. Similar to CDP-choline, magnesium threonate appears in only 1% of user stacks.
When it comes to magnesium threonate products, the ingredient to look for is Magtein, a specific type of magnesium threonate that has been shown to improve brain function in human clinical studies.
The SuppCo database contains numerous Magtein products. A few with top-level TrustScores include:
Metagenics Magtein Magnesium L-Threonate (9.56 Excellent)
Momentous Magtein Magnesium L-Threonate (9.50 Excellent)
Sports Research Magtein Magnesium L-Threonate (9.13 Excellent)
Bacopa Monnieri: The Mood and Memory Booster
While not quite as popular as omega-3s and magnesium among SuppCo users, bacopa monnieri does show up in just over 3% of stacks and 420 products.
Beyond boosting cognition, bacopa monnieri also has links to improved mood. Because who doesn't want to feel sharper and happier?
If you're interested in adding this cognition aid to your stack, we recommend:
TrustScore Pick: Thorne's Memoractive (9.69 Excellent) which contains a number of memory supportive nutrients alongside bacopa monnieri
Most Popular: Onnit's Alpha Brain Daily Cognitive Support (8.19 Very Good) that similarly showcases bacopa monnieri alongside other brain nutrients
Fisetin: The New Player
A new entrant to the brain health supplement space, fisetin’s use among the SuppCo community is similarly in its infancy.
Fisetin appears in just 92 products in SuppCo's 224,000 product database and only 2% of stacks. We're talking about a truly niche nutrient here—one that's just starting to gain traction.
Of the 92 products containing fisetin, most feature the nutrient alongside other longevity staples including NAD precursors, resveratrol, and quercetin.
Here are a few of the top fisetin containing products:
Designs for Health Senolytic Synergy (9.44 Excellent)
Life Extension's NAD+ Cell Regenerator and Resveratrol (8.31 Very Good)
The Takeaway
The data reveals a common pattern: the most established brain health supplements (omega-3s, turmeric curcumin) dominate user stacks, while the more specialized nutrients (CDP-choline, magnesium L-threonate, fisetin) remain niche picks for those doing deeper research.
Your brain deserves the same thoughtful approach you bring to the rest of your health. Our data shows that tens of thousands of SuppCo users are already prioritizing cognitive wellness—and we're here to help you do the same.
Whether you've already created an in-depth brain-support stack, or are just getting started on your brain health journey, we have the products, TrustScores, and Protocols to guide you on your way.
Call for Topics
Do you have topics or trends you'd like to see covered in this newsletter? Drop us a note at support@supp.co.
Fresh Additions
Here are a few brands we've added TrustScores for recently that offer products containing one of the brain health nutrients above:
Vital Nutrients: check out their CDP-Choline product
Adapt Naturals: check out their Luminous Mind product that contains CDP-choline and bacopa monnieri
Community
Help grow our community! Know someone who's concerned about keeping their mind sharp as they age? Share SuppCo with them—because brain health is a long-term game worth playing well.