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Immune Support

Protocol overview

Compare your current stack nutrients to the outlined protocol recommendations.

A well-functioning immune system is essential for overall health, protection against infections, and maintaining homeostasis in the body. The immune system is a complex network of cells, tissues, and signaling molecules that work together to identify and neutralize pathogens, regulate inflammation, and promote tissue repair. Supporting immune function through proper nutrition, lifestyle, and targeted supplementation can help optimize immune balance and enhance the body’s ability to adapt to various stressors.

A significant yet often overlooked aspect of immune health is the gut microbiome. The gut is home to nearly 70% of the body’s immune cells, making it a central hub for immune activity. A well-balanced gut microbiota plays a crucial role in training immune cells, regulating inflammatory responses, and preventing harmful pathogens from disrupting immune function. When gut health is compromised due to poor diet, stress, or environmental toxins, the immune system may become dysregulated, leading to increased susceptibility to infections, allergies, or chronic inflammation.

Several key nutrients and bioactive compounds play a central role in immune modulation. This protocol focuses on five well-researched components vitamin C, vitamin D, zinc, reishi mushroom, and immunoglobulin G (IgG) supplements. Each contributing uniquely to immune health through antioxidant support, cellular communication, pathogen defense, and immune regulation. Vitamin C and zinc are important for immune cell activation and reducing oxidative stress. Vitamin D plays a key role in immune signaling and supporting a balanced inflammatory response. Reishi mushroom contains bioactive polysaccharides that help modulate immune function, while IgG supplements support gut barrier integrity and promote immune surveillance.

This protocol integrates these essential nutrients to provide comprehensive immune support, helping to optimize immune function by addressing key mechanisms such as antioxidant protection, cellular defense, and gut-immune interactions in a constantly changing environment.

Last updated: Feb 13, 2025

5 Nutrients

D3

Vitamin D3

50mcg

Vitamin D interacts with immune cells, including macrophages, dendritic cells, and T lymphocytes, through vitamin D receptors. It plays a role in modulating inflammatory responses and supporting antimicrobial peptide production, and contributing to immune system regulation. [1]

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Zi

Zinc

15mg

Zinc is essential for immune function, supporting innate and adaptive responses. It plays a role in T-cell activation, cytokine regulation, and antioxidant defense. Zinc also contributes to maintaining immune cell integrity and function, influencing inflammatory balance and overall immune resilience. [2]

C

Vitamin C

1000mg

Vitamin C functions as a key antioxidant, contributing to cellular defense mechanisms and redox homeostasis. It plays a role in leukocyte function, collagen synthesis, and oxidative stress modulation, supporting physiological processes involved in immune surveillance and tissue integrity maintenance. [3]

Re

Reishi

157mg

Reishi (Ganoderma lucidum) is a medicinal mushroom rich in bioactive compounds such as polysaccharides, triterpenes, and beta-1,3/1,6-glucans, which may modulate immune function. Studies indicate that Reishi’s beta-glucans play a role in enhancing the activity of natural killer cells, T lymphocytes, and macrophages, contributing to a balanced and resilient immune response. [4]

IG

Immunoglobulin G

1500mg

Immunoglobulin G (IgG) supplements provide concentrated antibodies that may support immune balance by neutralizing pathogens and promoting gut barrier integrity. As the most abundant immunoglobulin, IgG helps regulate immune responses and may aid in reducing inflammatory burden and enhancing overall immune health. [5]

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Products

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Recommended for Zinc.
Servings
60
Price/serv
$0.20
From
$12.00
Format
capsule
Recommended for Reishi.
Servings
30
Price/serv
$1.02
From
$30.71
Format
capsule
Recommended for Vitamin C.
Servings
250
Price/serv
$0.21
From
$52.20
Format
capsule
Recommended for Vitamin D3.
Servings
60
Price/serv
$0.63
From
$37.99
Format
capsule
Recommended for Immunoglobulin G.
Servings
30
Price/serv
$2.63
From
$78.99
Format
scoop

Warnings

Do not take if you have known allergies to any of the ingredients. Avoid if you have an autoimmune condition without consulting a healthcare provider, as some ingredients may modulate immune activity. Do not take with immunosuppressive medications unless advised. If pregnant, nursing, or taking medications, consult a healthcare professional before use.

  1. Ghaseminejad-Raeini, A., Ghaderi, A., Sharafi, A., Nematollahi-Sani, B., Moossavi, M., Derakhshani, A., & Sarab, G. A. (2023). Immunomodulatory actions of vitamin D in various immune-related disorders: A comprehensive review. Frontiers in Immunology, 14, 950465. https://doi.org/10.3389/fimmu.2023.950465
  2. Gammoh, N. Z., & Rink, L. (2017). Zinc in infection and inflammation. Nutrients, 9(6), 624. https://doi.org/10.3390/nu9060624
  3. Carr, A. C., & Maggini, S. (2017). Vitamin C and immune function. Nutrients, 9(11), 1211. https://doi.org/10.3390/nu9111211
  4. Jin, X., Ruiz Beguerie, J., Sze, D. M., & Chan, G. C. (2016). Ganoderma lucidum (Reishi mushroom) for cancer treatment. Cochrane Database of Systematic Reviews, 2016(4), CD007731. https://doi.org/10.1002/14651858.CD007731.pub3
  5. Ulfman, L. H., Leusen, J. H. W., Savelkoul, H. F. J., Warner, J. O., & van Neerven, R. J. J. (2018). Effects of bovine immunoglobulins on immune function, allergy, and infection. Frontiers in Nutrition, 5, 52. https://doi.org/10.3389/fnut.2018.00052

These statements have not been evaluated by the Food and Drug Administration. Any products and informational content displayed on this page are not intended to diagnose, treat, cure, or prevent any disease.