Vanadium is a trace mineral that, while not classified as an essential nutrient, has garnered attention for its potential health benefits. This mineral is naturally found in various foods such as mushrooms, shellfish, black pepper, parsley, and grains, though it is typically present in very small amounts.
About Vanadium
- What is Vanadium?
- What is Vanadium used for, and what do the studies say?
- How does Vanadium work?
- How is Vanadium used differently in men’s and women’s health?
- How much Vanadium should I take?
- What are the main side effects of Vanadium?
- Who should not take Vanadium?
- Are Vanadium supplements known to interact with any medications?
- What are the best sources of Vanadium?
- What forms does Vanadium come in?
- Which sub-compounds of Vanadium, if any, are critical to the efficacy of Vanadium?
- What is Vanadium also known as?
- What is important to look for on the label of a Vanadium supplement to ensure product quality?
- Disclaimer & References
What is Vanadium?
Vanadium is a trace mineral that, while not classified as an essential nutrient, has garnered attention for its potential health benefits. This mineral is naturally found in various foods such as mushrooms, shellfish, black pepper, parsley, and grains, though it is typically present in very small amounts. Vanadium exists in several oxidation states, with vanadyl and vanadate being the most common forms found in biological systems.
In the human body, vanadium is stored mainly in bone tissues, as well as in the liver and kidneys. Although it is not required for human survival, vanadium may play a role in certain biochemical processes. Research has suggested that vanadium can influence glucose metabolism, potentially mimicking the actions of insulin and offering benefits related to blood sugar regulation.
The mineral's biochemical versatility makes it a subject of interest for ongoing research. Studies are investigating its potential roles in various metabolic processes and its impact on overall health. However, it is important to note that the body requires vanadium in very minute quantities, and the exact physiological necessity and mechanisms of action remain areas of active exploration.
What is Vanadium used for, and what do the studies say?
Vanadium is primarily studied for its potential impact on glucose metabolism and insulin sensitivity. Research has shown that vanadium compounds can mimic some of the biological actions of insulin, which has sparked interest in its potential benefits for maintaining healthy blood sugar levels. For instance, some studies suggest that vanadium may enhance the uptake of glucose into cells, thereby improving glycemic control. This has led to investigations into its possible use as a supplement for individuals looking to support balanced blood sugar levels [1].
In addition to its effects on glucose metabolism, vanadium has also been explored for its potential role in lipid metabolism. Preliminary studies indicate that vanadium may influence cholesterol levels, particularly by reducing low-density lipoprotein (LDL) cholesterol, often referred to as "bad" cholesterol. This potential benefit could contribute to cardiovascular health, although more comprehensive studies are needed to confirm these effects [2].
Beyond metabolic health, vanadium has been examined for its potential anti-inflammatory and antioxidant properties. Some animal studies have shown that vanadium compounds can reduce markers of inflammation and oxidative stress, which are critical factors in numerous chronic conditions. However, it's essential to approach these findings with caution, as the majority of the research has been conducted in animal models or in vitro, and human studies are still limited.
Overall, while the existing research on vanadium is promising, it is still in its early stages. The mineral's potential benefits for glucose and lipid metabolism, along with its anti-inflammatory properties, warrant further investigation through rigorous clinical trials to fully understand its efficacy and safety.
[1] Goldfine, A. B., & Simonson, D. C. (1999). Oral vanadyl sulfate improves insulin sensitivity in NIDDM but not in obese nondiabetic subjects. Diabetes, 48(2), 159-166. [2] Thompson, K. H., & Orvig, C. (2006). Vanadium in diabetes: 100 years from Phase 0 to Phase I. Journal of Inorganic Biochemistry, 100(12), 1925-1935.
How does Vanadium work?
Vanadium exerts its biological effects through several mechanisms, many of which are still under active investigation. One of the most well-documented actions of vanadium involves its ability to mimic insulin, a hormone crucial for regulating blood sugar levels. Vanadium compounds, such as vanadyl sulfate and sodium metavanadate, are thought to activate insulin receptors and enhance the translocation of glucose transporters to the cell membrane. This facilitates the uptake of glucose from the bloodstream into cells, thereby aiding in glucose metabolism [1].
At the molecular level, vanadium interacts with various enzymes and proteins involved in signal transduction pathways. For instance, it has been shown to inhibit protein tyrosine phosphatases (PTPs), which are enzymes that deactivate insulin signaling. By inhibiting PTPs, vanadium can prolong the activity of insulin receptors, thus enhancing insulin sensitivity and glucose uptake. This mechanism is particularly interesting because it suggests that vanadium could be useful in managing conditions characterized by insulin resistance [2].
Beyond its effects on glucose metabolism, vanadium is also believed to influence lipid metabolism. Studies indicate that vanadium can modulate the activity of enzymes involved in cholesterol synthesis and fatty acid metabolism. For example, some research suggests that vanadium can inhibit HMG-CoA reductase, the enzyme responsible for the synthesis of cholesterol in the liver. This inhibition could potentially lead to lower levels of LDL cholesterol, contributing to cardiovascular health [3].
Additionally, vanadium may exert antioxidant and anti-inflammatory effects. It has been shown to reduce oxidative stress by scavenging free radicals and enhancing the activity of antioxidant enzymes such as superoxide dismutase and catalase. This antioxidant action helps mitigate cellular damage and inflammation, which are underlying factors in many chronic diseases. However, it's important to note that most of these findings are based on animal studies or in vitro experiments, and more human research is needed to fully elucidate these mechanisms.
In summary, vanadium works through a multifaceted approach that includes mimicking insulin, enhancing glucose uptake, modulating lipid metabolism, and exerting antioxidant effects. These mechanisms collectively contribute to its potential health benefits, although further research is essential to fully understand its actions and applications.
[1] Goldfine, A. B., & Simonson, D. C. (1999). Oral vanadyl sulfate improves insulin sensitivity in NIDDM but not in obese nondiabetic subjects. Diabetes, 48(2), 159-166. [2] Thompson, K. H., & Orvig, C. (2006). Vanadium in diabetes: 100 years from Phase 0 to Phase I. Journal of Inorganic Biochemistry, 100(12), 1925-1935. [3] Brichard, S. M., & Henquin, J. C. (1995). The role of vanadium in the management of diabetes. Trends in Pharmacological Sciences, 16(8), 265-270.
How is Vanadium used differently in men’s and women’s health?
Vanadium's potential benefits are generally based on its effects on metabolic processes, which can be applicable to both men and women. However, there are nuances in how it might be utilized or studied with respect to gender-specific health concerns. While research on vanadium has not extensively focused on gender differences, there are some considerations worth noting.
For men, vanadium's role in glucose and lipid metabolism could be particularly relevant for conditions that are more prevalent or manifest differently in males. For example, men are often at higher risk for cardiovascular diseases at an earlier age compared to women. Studies have indicated that vanadium may help in reducing LDL cholesterol levels and improving lipid profiles, which could potentially support cardiovascular health in men. Additionally, since men are more likely to experience metabolic syndrome, characterized by a cluster of conditions including high blood sugar and abnormal cholesterol levels, vanadium's insulin-mimicking properties might offer some support [1].
In women's health, vanadium's influence on glucose metabolism can also be significant, especially considering conditions like polycystic ovary syndrome (PCOS), which is often associated with insulin resistance. Women with PCOS may benefit from vanadium's potential to improve insulin sensitivity and help regulate blood sugar levels. Additionally, women experience an increased risk of developing type 2 diabetes as they age, particularly after menopause. The potential glucose-regulating properties of vanadium could be an area of interest for supporting metabolic health in postmenopausal women [2].
Hormonal differences between men and women can also influence how vanadium is metabolized and utilized in the body. For instance, sex hormones like estrogen and testosterone may interact with vanadium in ways that could affect its efficacy and safety. Although this area is not well-studied, it highlights the need for gender-specific research to understand fully how vanadium supplementation might be optimized for men and women.
In summary, while vanadium's primary mechanisms of action related to glucose and lipid metabolism are beneficial for both men and women, the specific health concerns and hormonal interactions in each gender may influence its use and effectiveness. Further research is needed to explore these gender-specific effects comprehensively.
[1] Brichard, S. M., & Henquin, J. C. (1995). The role of vanadium in the management of diabetes. Trends in Pharmacological Sciences, 16(8), 265-270. [2] Diamanti-Kandarakis, E., & Dunaif, A. (2012). Insulin resistance and the polycystic ovary syndrome revisited: an update on mechanisms and implications. Endocrine Reviews, 33(6), 981-1030.
How much Vanadium should I take?
Determining the appropriate dosage of vanadium can be complex, as it largely depends on the form of vanadium being used, the specific health goals, and individual physiological factors. It's important to note that vanadium is not classified as an essential nutrient, and therefore, there is no established Recommended Dietary Allowance (RDA) for it. However, various studies and clinical trials have explored different dosages to assess its effects and safety.
In research contexts, typical dosages of vanadium supplements, such as vanadyl sulfate, range from 5 to 100 mg per day. For instance, some studies have used doses of 50 mg per day to explore the effects on glucose metabolism and insulin sensitivity [1]. Other trials have investigated lower doses, such as 10 to 30 mg per day, to examine potential benefits while minimizing side effects [2]. It's crucial to recognize that these dosages are used under controlled conditions with medical supervision.
The form of vanadium also plays a role in determining the appropriate dosage. Vanadyl sulfate and sodium metavanadate are among the most commonly studied forms, with varying bioavailability and potency. This means that 10 mg of vanadyl sulfate might not have the same physiological impact as 10 mg of another vanadium compound. Therefore, the specific form of vanadium being used should be considered when determining the dosage.
It's also important to highlight that the long-term safety of vanadium supplementation has not been well-established. While short-term studies suggest that vanadium can be tolerated at the dosages mentioned above, prolonged use at high doses could potentially lead to adverse effects. For this reason, some experts recommend starting with the lowest effective dose and closely monitoring for any side effects or changes in health status.
In summary, while various studies have explored dosages ranging from 5 to 100 mg per day, there is no one-size-fits-all recommendation for vanadium supplementation. The appropriate dosage depends on the specific form of vanadium, individual health goals, and personal health conditions. Consulting with a healthcare provider who can offer personalized advice based on the latest research and clinical guidelines is essential.
[1] Goldfine, A. B., & Simonson, D. C. (1999). Oral vanadyl sulfate improves insulin sensitivity in NIDDM but not in obese nondiabetic subjects. Diabetes, 48(2), 159-166. [2] Boden, G., & Chen, X. (1995). Effects of vanadyl sulfate on carbohydrate and lipid metabolism in patients with non-insulin-dependent diabetes mellitus. Metabolism, 44(3), 367-373.
What are the main side effects of Vanadium?
While vanadium supplementation has shown potential benefits, it is also associated with several side effects, particularly at higher doses or with prolonged use. Understanding these side effects is crucial for making informed decisions about vanadium supplementation.
One of the most commonly reported side effects of vanadium supplementation is gastrointestinal discomfort. Users often experience symptoms such as nausea, diarrhea, and stomach cramps. These symptoms tend to be more pronounced with higher doses of vanadium and can significantly impact the user's comfort and adherence to the supplementation regimen [1].
Another area of concern is the potential impact of vanadium on kidney function. Vanadium is primarily excreted through the kidneys, and high doses may place an additional burden on these organs. Some studies have suggested that long-term use of high-dose vanadium could potentially lead to nephrotoxicity, or damage to the kidneys, although more research is needed to fully understand this risk [2]. Therefore, individuals with pre-existing kidney conditions should be particularly cautious with vanadium supplementation.
Vanadium can also affect mineral balance in the body. For instance, it may interfere with the metabolism of other essential minerals like iron, zinc, and copper. This interference could potentially lead to deficiencies or imbalances in these critical nutrients, affecting overall health. Monitoring mineral levels during vanadium supplementation can help mitigate this risk.
There are also concerns about vanadium's impact on neurocognitive function. Some animal studies have indicated that high doses of vanadium can lead to neurological symptoms such as mood changes, irritability, and cognitive deficits. While these effects have primarily been observed in animal models, they raise important questions about the long-term safety of vanadium supplementation in humans [3].
In summary, while vanadium has potential health benefits, it is also associated with several side effects, including gastrointestinal discomfort, potential kidney strain, interference with mineral balance, and possible neurocognitive effects. These side effects underscore the importance of using vanadium cautiously and under medical supervision, especially at higher doses or for extended periods.
[1] Goldfine, A. B., & Simonson, D. C. (1999). Oral vanadyl sulfate improves insulin sensitivity in NIDDM but not in obese nondiabetic subjects. Diabetes, 48(2), 159-166. [2] Domingo, J. L. (1996). Vanadium and tungsten derivatives as antidiabetic agents: a review of their toxic effects. Biological Trace Element Research, 55(3), 183-201. [3] Ivancsits, S., Pilger, A., Diem, E., Schaffer, A., & Rüdiger, H. W. (2002). Vanadate induces DNA strand breaks in cultured human fibroblasts at doses relevant to occupational exposure. Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 514(1-2), 79-92.
Who should not take Vanadium?
While vanadium supplementation may offer potential benefits, it is not suitable for everyone. Certain individuals should exercise caution or avoid vanadium altogether due to potential risks and contraindications.
Firstly, individuals with pre-existing kidney conditions should be particularly cautious with vanadium supplementation. Vanadium is primarily excreted through the kidneys, and high doses can place an additional burden on these organs. People with compromised kidney function are at a higher risk of nephrotoxicity, which refers to kidney damage. Therefore, it's crucial for anyone with kidney issues to consult a healthcare provider before considering vanadium.
Pregnant and breastfeeding women should also avoid vanadium supplements. There is limited research on the safety of vanadium during pregnancy and lactation, and the potential risks to the developing fetus or nursing infant are not well-understood. Until more comprehensive studies are available, it is generally recommended that pregnant and breastfeeding women refrain from using vanadium supplements to avoid any potential adverse effects.
Children and adolescents should also avoid vanadium supplementation. The long-term effects of vanadium on growth and development have not been well-studied, and the risk of potential side effects may outweigh any potential benefits. Pediatric populations are particularly sensitive to nutrient imbalances, and the safety profile of vanadium in these age groups has not been adequately established.
Individuals with certain metabolic conditions, such as hemochromatosis (a condition characterized by excessive iron accumulation in the body), should be cautious as well. Vanadium can interfere with the metabolism of other essential minerals like iron, zinc, and copper, potentially exacerbating these conditions. Similarly, people with other mineral imbalances or deficiencies should consult a healthcare provider before taking vanadium, as it could further disrupt their mineral status.
Lastly, those who are on specific medications should be aware of potential interactions with vanadium. While this will be discussed in more detail later, it is essential to consider that vanadium could interact with medications that affect blood sugar levels, among others. Individuals on such medications should consult their healthcare provider to evaluate the risk of interactions.
In summary, vanadium supplementation is not recommended for individuals with kidney issues, pregnant or breastfeeding women, children and adolescents, people with specific metabolic conditions, and those on certain medications. Consulting a healthcare provider is essential to evaluate individual risks and benefits before starting vanadium supplementation.
Are Vanadium supplements known to interact with any medications?
Vanadium supplements have the potential to interact with various medications, which is an important consideration for anyone thinking about adding this mineral to their regimen. Understanding these interactions can help manage potential risks and optimize the benefits of both the supplement and any concurrent medications.
One of the primary areas of concern is the interaction between vanadium and medications used to manage blood sugar levels, such as insulin and oral hypoglycemic agents. Given that vanadium can mimic insulin and enhance insulin sensitivity, taking it alongside these medications could potentiate their effects. This could lead to an increased risk of hypoglycemia, a condition characterized by abnormally low blood sugar levels. Symptoms of hypoglycemia can include dizziness, confusion, sweating, and in severe cases, loss of consciousness. Therefore, individuals on diabetes medications should be cautious and consult with their healthcare provider before starting vanadium supplements [1].
Vanadium may also interact with anticoagulant and antiplatelet medications, which are used to prevent blood clotting. Some studies suggest that vanadium can influence platelet aggregation and blood coagulation. While the exact mechanism is not fully understood, this interaction could potentially enhance the effects of anticoagulant medications, increasing the risk of bleeding and bruising. Individuals on medications such as warfarin, heparin, or aspirin should be particularly vigilant and discuss the use of vanadium with their healthcare provider [2].
Another potential interaction is with nonsteroidal anti-inflammatory drugs (NSAIDs). Vanadium has been shown to have anti-inflammatory properties, and combining it with NSAIDs could amplify these effects. While this might seem beneficial, it could also lead to increased gastrointestinal irritation or other side effects commonly associated with NSAID use. Monitoring for any adverse effects is essential if vanadium is taken alongside NSAIDs [3].
Moreover, vanadium can interfere with the absorption and metabolism of certain essential minerals, such as iron, zinc, and copper. This interaction might affect individuals who are taking mineral supplements or medications that influence mineral metabolism. For example, people on iron supplements or medications for treating anemia should be aware that vanadium might alter the effectiveness of these treatments.
In summary, vanadium supplements can interact with various medications, including those for managing blood sugar levels, anticoagulants, NSAIDs, and mineral supplements. These interactions underscore the importance of consulting with a healthcare provider to evaluate potential risks and benefits, particularly for individuals on these medications.
[1] Goldfine, A. B., & Simonson, D. C. (1999). Oral vanadyl sulfate improves insulin sensitivity in NIDDM but not in obese nondiabetic subjects. Diabetes, 48(2), 159-166. [2] Thompson, K. H., & Orvig, C. (2003). Metal complexes in medicinal chemistry: New vistas and challenges in drug design. Chemical Reviews, 103(3), 4307-4381. [3] Domingo, J. L. (1996). Vanadium and tungsten derivatives as antidiabetic agents: a review of their toxic effects. Biological Trace Element Research, 55(3), 183-201.
What are the best sources of Vanadium?
Vanadium is naturally found in a variety of foods, though typically in trace amounts. Including these foods in your diet can help you obtain small quantities of this mineral, which may contribute to overall health. Here are some of the best dietary sources of vanadium:
- Mushrooms: Certain types of mushrooms, such as shiitake and white button mushrooms, are known to contain vanadium. These fungi not only provide vanadium but also offer other beneficial nutrients like vitamin D, antioxidants, and fiber.
- Shellfish: Seafood, particularly shellfish such as oysters, crabs, and lobsters, are good sources of vanadium. Including shellfish in your diet can help you obtain vanadium along with other essential nutrients like zinc, selenium, and omega-3 fatty acids.
- Whole Grains: Whole grains like oats, barley, and brown rice also contain small amounts of vanadium. These grains are rich in fiber, vitamins, and minerals, making them a nutritious addition to your diet.
- Black Pepper: Surprisingly, black pepper is a notable source of vanadium. This common spice can easily be incorporated into your daily meals, providing not just flavor but also a small dose of vanadium.
- Parsley: This herb, often used as a garnish or seasoning, contains vanadium. Parsley is also rich in vitamins A, C, and K, making it a healthy and versatile addition to various dishes.
- Vegetables: Some vegetables, including leafy greens like spinach and kale, as well as root vegetables like carrots and potatoes, contain trace amounts of vanadium. These vegetables are also packed with other essential nutrients and antioxidants.
- Dairy Products: Milk and its derivatives, such as cheese and yogurt, provide small amounts of vanadium. Dairy products are also excellent sources of calcium, vitamin D, and protein.
- Meat and Poultry: While not as rich in vanadium as some other sources, meat and poultry do contain trace amounts. These foods also provide essential amino acids, iron, and B vitamins.
It’s important to note that the vanadium content in these foods can vary based on factors such as soil quality and food processing methods. While dietary sources can provide some vanadium, the amounts are generally quite small compared to those found in supplements.
In summary, mushrooms, shellfish, whole grains, black pepper, parsley, vegetables, dairy products, and meat and poultry are among the best dietary sources of vanadium. Incorporating a variety of these foods into your diet can help you obtain this trace mineral along with a host of other essential nutrients.
What forms does Vanadium come in?
Vanadium is available in several forms, each with distinct characteristics that can influence its bioavailability and efficacy. Here are the most common forms of vanadium found in dietary supplements and their respective attributes:
- Vanadyl Sulfate: This is one of the most commonly used forms of vanadium in supplements. Vanadyl sulfate is known for its relatively high bioavailability, which means it is more easily absorbed by the body compared to other forms. It has been extensively studied for its potential effects on glucose metabolism and insulin sensitivity. Due to its widespread use in research, vanadyl sulfate is often the preferred form for those looking to support blood sugar regulation.
- Sodium Metavanadate: Another popular form, sodium metavanadate, is often used in both research and commercial supplements. This form of vanadium is also relatively bioavailable and has been studied for its potential metabolic benefits. Sodium metavanadate is typically used in lower doses compared to vanadyl sulfate because it can be more potent.
- Vanadium Pentoxide: Vanadium pentoxide is another form that is sometimes used in supplements, although it is less common. This form of vanadium is primarily used in industrial applications, but it has also been explored for its biological effects. However, vanadium pentoxide is less bioavailable and may have a higher potential for toxicity, making it less suitable for dietary supplementation.
- Bis(maltolato)oxovanadium(IV) (BMOV): This is a more specialized form of vanadium that has been synthesized to improve bioavailability and reduce toxicity. BMOV is a chelated form of vanadium, meaning it is bound to organic molecules (maltol) to enhance absorption and minimize side effects. This form has shown promise in preliminary studies for its potential benefits in glucose metabolism and insulin sensitivity.
- Ammonium Vanadate: Although not commonly used in dietary supplements, ammonium vanadate has been studied for its biological effects. This form is primarily used in scientific research rather than for consumer supplementation due to its variable bioavailability and potential for side effects.
- Organic Vanadium Complexes: Researchers have explored various organic complexes of vanadium to improve its bioavailability and reduce toxicity. These complexes involve binding vanadium to organic molecules, such as amino acids or peptides, to enhance its absorption and efficacy. While these forms are still largely in the experimental stage, they represent a promising area of research.
In summary, vanadium supplements come in various forms, including vanadyl sulfate, sodium metavanadate, vanadium pentoxide, BMOV, ammonium vanadate, and organic vanadium complexes. Each form has distinct characteristics that affect its bioavailability and potential health benefits. Among these, vanadyl sulfate and sodium metavanadate are the most commonly used and studied forms.
Which sub-compounds of Vanadium, if any, are critical to the efficacy of Vanadium?
The efficacy of vanadium as a supplement is influenced significantly by the specific sub-compounds in which it is formulated. These sub-compounds affect the bioavailability, potency, and safety profile of vanadium. Among the various vanadium compounds, several have been studied extensively for their potential health benefits and are considered critical to its efficacy:
- Vanadyl Sulfate (VOSO4): Vanadyl sulfate is perhaps the most widely researched form of vanadium. It is known for its relatively high bioavailability and has been shown to mimic insulin, thereby influencing glucose metabolism and insulin sensitivity. Studies have demonstrated that vanadyl sulfate can improve glycemic control in individuals with insulin resistance or type 2 diabetes, making it a critical sub-compound for metabolic health applications [1].
- Sodium Metavanadate (NaVO3): Sodium metavanadate is another important sub-compound of vanadium. It shares similar insulin-mimicking properties with vanadyl sulfate and has been studied for its effects on glucose and lipid metabolism. Sodium metavanadate is potent and effective in lower doses compared to some other forms, which can be advantageous for minimizing potential side effects while achieving desired outcomes [2].
- Bis(maltolato)oxovanadium(IV) (BMOV): BMOV is a chelated form of vanadium designed to enhance bioavailability and reduce toxicity. This sub-compound has shown promise in preclinical and clinical studies for its ability to improve insulin sensitivity and support metabolic health. The chelation process, which involves binding vanadium to organic molecules like maltol, helps improve its absorption and efficacy while minimizing gastrointestinal discomfort and other side effects [3].
- Vanadium Pentoxide (V2O5): Although less common in dietary supplements due to concerns about toxicity, vanadium pentoxide has been used in some research contexts. It is primarily of interest for its potential biological effects, but its lower bioavailability and higher risk of adverse effects make it less suitable for general supplementation. Therefore, its role in the efficacy of vanadium supplements is limited compared to other sub-compounds [4].
- Vanadate (VO4³⁻) Compounds: Vanadate ions are another form of vanadium that can influence biological processes. These compounds can inhibit protein tyrosine phosphatases (PTPs), thereby enhancing insulin signaling. While less frequently used in commercial supplements, vanadate compounds are critical to understanding the broader mechanisms through which vanadium exerts its effects on glucose metabolism and other cellular functions [5].
The choice of sub-compound can significantly impact the effectiveness and safety of vanadium supplementation. Vanadyl sulfate, sodium metavanadate, and BMOV are among the most effective and well-tolerated forms, making them critical to the efficacy of vanadium as a supplement. These sub-compounds have been extensively studied for their metabolic benefits and offer a balance between potency and safety.
[1] Goldfine, A. B., & Simonson, D. C. (1999). Oral vanadyl sulfate improves insulin sensitivity in NIDDM but not in obese nondiabetic subjects. Diabetes, 48(2), 159-166. [2] Thompson, K. H., & Orvig, C. (2006). Vanadium in diabetes: 100 years from Phase 0 to Phase I. Journal of Inorganic Biochemistry, 100(12), 1925-1935. [3] McNeill, J. H., Yuen, V. G., Hoveyda, H. R., & Orvig, C. (1992). Bis(maltolato)oxovanadium(IV) is a potent insulin mimic. Journal of Medicinal Chemistry, 35(9), 1489-1491. [4] Domingo, J. L. (1996). Vanadium and tungsten derivatives as antidiabetic agents: a review of their toxic effects. Biological Trace Element Research, 55(3), 183-201. [5] Brichard, S. M., & Henquin, J. C. (1995). The role of vanadium in the management of diabetes. Trends in Pharmacological Sciences, 16(8), 265-270.
What is Vanadium also known as?
Vanadium is known by various names, chemical compounds, and abbreviations. Here is a comprehensive list that includes common misspellings, alternative names, and related compounds:
- Chemical Name and Symbol:
- Vanadium (V)
- Atomic number 23
- Common Compounds:
- Vanadyl Sulfate (VOSO4)
- Sodium Metavanadate (NaVO3)
- Vanadium Pentoxide (V2O5)
- Bis(maltolato)oxovanadium(IV) (BMOV)
- Ammonium Vanadate ((NH4VO3))
- Vanadate (VO4³⁻)
- Alternative Names:
- Vanadyl
- Metavanadate
- Vanadium(IV) oxide
- Vanadium(V) oxide
- Common Misspellings and Abbreviations:
- Vanadum
- Vandium
- Vanidium
- Vanidum
- Trade Names and Supplement Labels:
- Vanadyl Complex
- Vanadyl Sulfate Capsules
- Blood Sugar Support with Vanadyl Sulfate
- Glucose Metabolism Support with Vanadium
- Synonyms in Scientific Contexts:
- Dioxovanadium
- Tetravalent vanadium
- Pentavalent vanadium
- Related Elements and Compounds:
- Transition metal
- Elemental vanadium
- Vanadium oxides (e.g., VO2, V2O3)
Understanding these various names and forms is crucial for anyone researching or considering vanadium supplementation, as it can appear on supplement labels and scientific literature in different contexts. Being aware of these synonyms and related compounds can help in identifying the appropriate form and understanding the broader scope of vanadium's applications and effects.
What is important to look for on the label of a Vanadium supplement to ensure product quality?
When selecting a vanadium supplement, it's important to carefully examine the product label to ensure quality, safety, and efficacy. Here are key factors to look for:
- Form of Vanadium:
- Ensure the supplement specifies the form of vanadium it contains, such as vanadyl sulfate, sodium metavanadate, or bis(maltolato)oxovanadium(IV) (BMOV). Different forms have varying bioavailability and potency, so it's crucial to know which form you are taking.
- Dosage and Concentration:
- Check the amount of vanadium per serving. Dosages can vary widely, typically ranging from 5 to 100 mg per day. Ensure that the dosage aligns with what has been studied and recommended for your specific health goals.
- Other Ingredients:
- Review the list of inactive ingredients or excipients. These can include fillers, binders, and preservatives. Choose supplements with minimal, high-quality, and non-allergenic additives.
- Third-Party Testing:
- Look for certifications or seals from third-party testing organizations such as NSF International, USP (United States Pharmacopeia), or ConsumerLab. These certifications indicate that the product has been tested for purity, potency, and safety.
- Manufacturing Standards:
- Ensure the product is manufactured in a facility that follows Good Manufacturing Practices (GMP). This information is often indicated on the label and ensures that the supplement is produced in a clean, controlled environment.
- Country of Origin:
- Check where the supplement is manufactured. Products made in countries with stringent regulatory standards, such as the United States, Canada, or countries in the European Union, are generally more reliable.
- Expiration Date:
- Verify the expiration date to ensure the supplement is fresh and effective. Avoid products that are close to or past their expiration date.
- Allergen Information:
- Check for any potential allergens listed on the label, such as gluten, soy, dairy, or nuts, especially if you have specific dietary restrictions or allergies.
- Brand Reputation:
- Choose supplements from reputable brands with positive reviews and a history of quality. Research the company to ensure they have a good track record and customer feedback.
- Serving Size and Directions:
- Follow the recommended serving size and usage instructions provided on the label. It’s important to adhere to these guidelines to ensure safe and effective use of the supplement.
By paying attention to these details on the label, you can make a more informed decision and select a high-quality vanadium supplement that meets your needs and safety standards.
Disclaimer & References
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