Ec

Echinacea, commonly known as coneflower, is a genus of herbaceous flowering plants in the daisy family, Asteraceae. It is native to North America and thrives in open wooded areas, prairies, and dry plains.



What is Echinacea?

Echinacea, commonly known as coneflower, is a genus of herbaceous flowering plants in the daisy family, Asteraceae. It is native to North America and thrives in open wooded areas, prairies, and dry plains. The genus Echinacea comprises several species, but the most commonly used for health and wellness purposes are Echinacea purpurea, Echinacea angustifolia, and Echinacea pallida.

The plant is characterized by its distinctive large, daisy-like flowers with a prominent central cone, which is usually spiny and raised, surrounded by drooping petals that can range in color from purple to pink. The name "Echinacea" is derived from the Greek word "echinos," meaning hedgehog, a reference to the plant's spiny central cone.

Historically, Echinacea has been used by Native American tribes for a variety of medicinal purposes. They utilized different parts of the plant, including the roots, flowers, and leaves, to prepare teas, tinctures, and poultices for treating infections, wounds, and other ailments. In modern times, Echinacea has gained popularity as a herbal supplement, particularly for its purported immune-boosting properties.

Back to table of contents


What is Echinacea used for, and what do the studies say?

Echinacea is widely recognized and utilized for its potential benefits in supporting the immune system. It is most commonly used to prevent and treat symptoms of the common cold and other upper respiratory tract infections (URTIs). Many people turn to Echinacea supplements at the first sign of a cold, hoping to reduce the severity and duration of symptoms such as sore throat, runny nose, and fever.

The scientific community has extensively studied Echinacea, but the results are somewhat mixed. Several studies suggest that Echinacea may provide modest benefits in reducing the incidence and duration of colds. For instance, a meta-analysis published in "The Lancet Infectious Diseases" found that Echinacea decreased the odds of developing the common cold by 58% and shortened the duration of a cold by 1.4 days. Another study published in "Phytotherapy Research" indicated that a proprietary Echinacea extract enhanced systemic immune response during a cold, potentially leading to faster symptom resolution.

However, not all research supports these findings. A study published in the "Annals of Internal Medicine" found that Echinacea did not significantly reduce the duration or severity of cold symptoms in young, healthy adults when compared to a placebo. Similarly, a Cochrane review concluded that while there might be a weak benefit from some Echinacea products, the overall evidence does not convincingly support its effectiveness in treating or preventing colds.

In summary, while some studies suggest that Echinacea can help reduce the incidence and duration of common colds, the evidence is inconsistent. The variability in study results may be due to differences in Echinacea species, preparation methods, dosages, and study designs.

Back to table of contents


How does Echinacea work?

Echinacea is believed to exert its effects primarily through its action on the immune system. The plant contains a variety of bioactive compounds, including alkamides, glycoproteins, polysaccharides, and caffeic acid derivatives, which are thought to play a role in its immunomodulatory properties. These compounds may help enhance the body's natural defense mechanisms, making it more effective at warding off pathogens.

One of the primary ways Echinacea is thought to work is by stimulating the activity of white blood cells, particularly macrophages, natural killer (NK) cells, and neutrophils. These cells are crucial components of the immune system that help identify and eliminate pathogens such as viruses and bacteria. A study published in "Phytotherapy Research" found that Echinacea increased the number of circulating white blood cells, monocytes, neutrophils, and NK cells in volunteers experiencing a common cold, suggesting an enhancement of the non-specific immune response.

Additionally, Echinacea has been shown to possess anti-inflammatory properties. For example, a standardized extract of Echinacea purpurea, known as Echinaforce, has demonstrated the ability to reduce the production of pro-inflammatory cytokines, which are signaling molecules that mediate inflammation. This dual action—boosting immune cell activity and reducing inflammation—may help to alleviate symptoms associated with upper respiratory tract infections.

Another possible mechanism involves Echinacea's antioxidant properties. Some studies indicate that Echinacea can scavenge free radicals and reduce oxidative stress, which can contribute to its overall immune-supporting effects. By mitigating oxidative damage, Echinacea may help maintain cellular integrity and function, further supporting the immune response.

In summary, Echinacea's potential benefits are thought to arise from its ability to enhance immune cell activity, reduce inflammation, and exhibit antioxidant properties. These combined effects may help the body more effectively respond to and recover from infections. However, it's important to note that the exact mechanisms and the extent of these effects can vary depending on the specific Echinacea preparation and individual response.

Back to table of contents


How is Echinacea used differently in men’s and women’s health?

Echinacea is generally used similarly by both men and women, primarily for its potential immune-boosting properties and its ability to help prevent and treat symptoms of the common cold and other upper respiratory tract infections. However, there are some nuances and specific areas where Echinacea might intersect with gender-specific health concerns.

For women, Echinacea has been explored in the context of urinary tract infections (UTIs), which are more prevalent in women than in men. Some preliminary studies and anecdotal evidence suggest that Echinacea, due to its immune-enhancing and anti-inflammatory properties, might help reduce the frequency of recurrent UTIs. However, more robust clinical trials are needed to confirm these potential benefits.

In men, Echinacea has not been widely studied for specific male health issues. However, men might use Echinacea similarly to women for general immune support and to manage symptoms of colds and respiratory infections. Additionally, some men might explore Echinacea for its potential to reduce inflammation, which could be beneficial in managing chronic inflammation-related conditions that are more common in men, such as certain cardiovascular issues.

Athletes of both genders may find Echinacea beneficial for its potential to modulate mucosal immunity. A study published in the "International Journal of Sports Medicine" indicated that Echinacea might help attenuate the immune suppression that often follows intense exercise, potentially reducing the duration of upper respiratory tract infections. This can be particularly relevant for athletes who are at higher risk of infections due to intense training regimens.

Lastly, hormonal differences between men and women could potentially influence how Echinacea works in the body, although this area has not been extensively studied. For instance, women might experience fluctuations in immune function related to their menstrual cycle, pregnancy, or menopause, which could theoretically alter the effectiveness of Echinacea. Conversely, men might experience different inflammatory responses due to higher levels of testosterone, which could also influence how Echinacea works for them.

In conclusion, while the primary use of Echinacea for immune support is consistent across genders, there are specific contexts and health concerns where Echinacea might offer additional benefits for men and women. However, more targeted research is needed to fully understand these gender-specific effects.

Back to table of contents


How much Echinacea should I take?

Determining the appropriate dosage of Echinacea can be challenging due to the variability in the formulations and preparations available. The dosage largely depends on the specific Echinacea product being used, as well as the intended purpose—whether for prevention or treatment of symptoms.

For general immune support and prevention of upper respiratory tract infections, common dosages for Echinacea purpurea extracts range from 300 to 500 milligrams taken three times daily. This dosage has been used in several studies and is typically sufficient for maintaining immune health. However, different products may have different concentrations of active compounds, so it's essential to follow the manufacturer's instructions on the label.

When using Echinacea at the onset of cold symptoms, higher doses are often recommended. For example, studies have used doses of up to 3,000 milligrams per day in divided doses during the first 24 to 48 hours of symptom onset. A study published in the "Annals of Internal Medicine" utilized a dose of 1 gram (1,000 milligrams) taken four times on the first day, followed by 500 milligrams three times daily for up to 10 days. This regimen aimed to provide a strong initial boost to the immune system to help mitigate the severity and duration of cold symptoms.

For liquid extracts or tinctures, the dosage can vary significantly. A typical dosage might be 2.5 milliliters taken three times daily. Some tinctures might recommend a single dose of 5 milliliters taken at the first sign of symptoms, followed by smaller doses throughout the day. Again, it's crucial to adhere to the specific dosing instructions provided by the product manufacturer.

When considering Echinacea for children, the dosage should be adjusted based on the child's age and weight. Pediatric formulations are available, and these generally provide dosing guidelines appropriate for children. For instance, a study published in the "Journal of Alternative and Complementary Medicine" used Echinacea purpurea extract dosed at 1 milliliter three times daily for children aged 2 to 11 years.

It's important to note that while Echinacea is generally considered safe for short-term use, long-term use is less well-studied, and continuous use beyond 8 to 12 weeks is not typically recommended without professional guidance. Always consult the product label and consider seeking advice from a healthcare professional to ensure the dosage is appropriate for your specific needs and health status.

Back to table of contents


What are the main side effects of Echinacea?

Echinacea is generally considered safe for most people when used as directed, but like any supplement, it can cause side effects in some individuals. The most commonly reported side effects are relatively mild and may include gastrointestinal symptoms such as nausea, stomach pain, or diarrhea. Some people may also experience an unpleasant taste if taking liquid formulations or tinctures.

Allergic reactions to Echinacea are another potential side effect, particularly in individuals who are allergic to plants in the daisy family (Asteraceae), which includes ragweed, chrysanthemums, marigolds, and daisies. Allergic reactions can range from mild skin rashes to more severe reactions like anaphylaxis, although the latter is rare. If you have a known allergy to any of these plants, it's advisable to avoid Echinacea or consult a healthcare provider before using it.

Some studies have noted that Echinacea can cause mild to moderate skin reactions, including rash, itching, and swelling. A study published in the "Annals of Internal Medicine" observed these types of skin reactions in a small number of participants. These reactions are generally not severe but can be uncomfortable and may require discontinuation of the supplement.

Respiratory symptoms like shortness of breath and wheezing have also been reported, although these are uncommon. If you experience any difficulty breathing or other severe respiratory symptoms, it's important to seek medical attention immediately.

In some instances, particularly with long-term use, Echinacea might affect liver enzyme levels. While this is not commonly reported and the clinical significance is unclear, it suggests that individuals with liver conditions or those taking medications metabolized by the liver should exercise caution and consult a healthcare provider before using Echinacea.

Lastly, while not a side effect per se, it's worth noting that Echinacea's efficacy and safety profile can vary widely depending on the specific product and formulation used. This is due to differences in species, plant parts used, preparation methods, and concentrations of active compounds. Therefore, choosing a high-quality, standardized product from a reputable manufacturer is crucial to minimize potential side effects and ensure efficacy.

In summary, while Echinacea is generally safe for short-term use, some individuals may experience mild gastrointestinal symptoms, allergic reactions, skin rashes, and, rarely, respiratory symptoms. If you have any pre-existing conditions or concerns, consulting a healthcare provider before starting Echinacea is always a prudent approach.

Back to table of contents


Who should not take Echinacea?

While Echinacea is generally considered safe for most people, certain individuals should avoid using it due to potential risks and contraindications. Here are some groups of people who should exercise caution or avoid Echinacea altogether:

  1. Individuals with Allergies to the Asteraceae Family: People who are allergic to plants in the Asteraceae family, which includes ragweed, chrysanthemums, marigolds, and daisies, are at a higher risk of experiencing allergic reactions to Echinacea. Allergic reactions can range from mild skin rashes to severe anaphylaxis, although the latter is rare. If you have a known allergy to any of these plants, it's best to avoid Echinacea or consult a healthcare provider before use.
  2. People with Autoimmune Disorders: Echinacea is known for its immune-stimulating properties, which may not be suitable for individuals with autoimmune disorders such as lupus, rheumatoid arthritis, multiple sclerosis, or other autoimmune conditions. In these cases, stimulating the immune system could potentially exacerbate symptoms or trigger flare-ups. Therefore, individuals with autoimmune disorders should consult their healthcare provider before using Echinacea.
  3. Those with Progressive Systemic Diseases: People with progressive systemic diseases like tuberculosis, sarcoidosis, or any form of chronic infection should avoid Echinacea. The immune-modulating effects of Echinacea could interfere with the management of these conditions and potentially worsen symptoms.
  4. Individuals Taking Immunosuppressive Medications: Since Echinacea stimulates the immune system, it may counteract the effects of immunosuppressive medications. This is particularly relevant for individuals who have undergone organ transplants or are being treated for autoimmune diseases. Combining Echinacea with immunosuppressive drugs could reduce the efficacy of these medications and compromise their intended therapeutic effects.
  5. Pregnant and Breastfeeding Women: The safety of Echinacea for pregnant and breastfeeding women has not been well-established through rigorous clinical trials. While some studies suggest that short-term use may be safe, the lack of comprehensive data means it is generally recommended that pregnant and breastfeeding women avoid Echinacea unless advised otherwise by a healthcare provider.
  6. Children: While some pediatric formulations of Echinacea exist, the safety and efficacy for children, particularly young children, are not well-documented. Echinacea should be used with caution in children and only under the guidance of a healthcare provider.
  7. Individuals with Liver Disorders: There is some evidence to suggest that long-term use of Echinacea can affect liver enzyme levels. Individuals with liver conditions or those taking medications that are metabolized by the liver should use Echinacea cautiously and consult their healthcare provider to avoid potential liver-related complications.

In conclusion, while Echinacea can offer benefits for many people, individuals with allergies to the Asteraceae family, autoimmune disorders, progressive systemic diseases, those taking immunosuppressive medications, pregnant and breastfeeding women, children, and those with liver disorders should approach Echinacea with caution and consult a healthcare provider before use.

Back to table of contents


Are Echinacea supplements known to interact with any medications?

Echinacea supplements can interact with certain medications, potentially altering their effects or leading to adverse reactions. It's essential to be aware of these interactions if you're considering adding Echinacea to your supplement regimen. Here are some key interactions to be mindful of:

  1. Immunosuppressive Medications: Echinacea is known for its immune-boosting properties, which can counteract the effects of immunosuppressive drugs. These medications are often prescribed to individuals who have undergone organ transplants, or those being treated for autoimmune disorders. Echinacea could potentially reduce the effectiveness of drugs such as cyclosporine, tacrolimus, and corticosteroids, making them less effective at suppressing the immune system and increasing the risk of organ rejection or disease flare-ups.
  2. Hepatotoxic Drugs: Some evidence suggests that long-term use of Echinacea might affect liver enzyme levels. Therefore, combining Echinacea with medications that are metabolized by the liver, such as acetaminophen, statins, or certain antifungals (like ketoconazole), could increase the risk of liver toxicity. If you have liver conditions or are taking hepatotoxic medications, it's crucial to consult a healthcare provider before using Echinacea.
  3. Medications Metabolized by Cytochrome P450 Enzymes: Echinacea can affect the activity of cytochrome P450 enzymes, particularly CYP3A4 and CYP1A2. These enzymes are responsible for the metabolism of many drugs, including certain antidepressants, antipsychotics, anticoagulants, and anticonvulsants. By influencing these enzymes, Echinacea can either increase or decrease the blood levels of these medications, potentially leading to reduced efficacy or increased risk of side effects. Examples include medications like warfarin, clozapine, and diazepam.
  4. Caffeine: Echinacea may slow the breakdown of caffeine in the body, leading to increased levels of caffeine and prolonged stimulant effects. This could result in side effects such as jitteriness, headache, and sleep disturbances. If you consume large amounts of caffeine or are sensitive to its effects, be cautious when using Echinacea.
  5. Antifungal Medications: Some antifungal medications, like ketoconazole, are metabolized by the liver and can interact with Echinacea. The combination may increase the risk of liver toxicity and affect the efficacy of the antifungal treatment. It's essential to consult a healthcare provider if you are undergoing treatment with antifungal medications and considering Echinacea supplementation.
  6. Certain Chemotherapy Drugs: Echinacea's immune-stimulating properties might interfere with the effectiveness of some chemotherapy drugs. While research in this area is limited, it's generally advised for cancer patients undergoing chemotherapy to avoid Echinacea unless specifically recommended by their oncologist.

In summary, Echinacea can interact with various medications, including immunosuppressive drugs, hepatotoxic medications, drugs metabolized by cytochrome P450 enzymes, caffeine, antifungal medications, and certain chemotherapy drugs. If you are taking any prescription medications or have any underlying health conditions, it is crucial to consult with a healthcare provider before adding Echinacea to your regimen. This will help ensure that you avoid potential interactions and use the supplement safely and effectively.

Back to table of contents


What are the best sources of Echinacea?

When considering Echinacea supplements, it’s important to choose high-quality products from reputable sources to ensure efficacy and safety. The best sources of Echinacea will typically adhere to stringent manufacturing practices, provide clear labeling, and have undergone third-party testing. Here are some factors to consider and recommendations for finding the best sources of Echinacea:

  1. Reputable Brands: Look for well-known brands that have a solid reputation for quality and transparency. Established companies are more likely to comply with Good Manufacturing Practices (GMP) and have rigorous quality control measures in place. Brands that are transparent about their sourcing, manufacturing processes, and ingredient quality are generally more trustworthy.
  2. Standardized Extracts: Choose Echinacea supplements that are standardized to contain specific amounts of active compounds, such as alkamides, polysaccharides, and cichoric acid. Standardization ensures a consistent level of active ingredients in each dose, which can enhance the supplement's effectiveness. For example, some products may specify the percentage of alkamides or polysaccharides, which are key active constituents.
  3. Third-Party Testing: Opt for products that have been independently tested by third-party laboratories. Third-party testing verifies the purity, potency, and safety of the supplement, ensuring that it is free from contaminants such as heavy metals, pesticides, and microbial impurities. Certifications from organizations like NSF International, US Pharmacopeia (USP), or ConsumerLab can provide added assurance of quality.
  4. Clear Labeling: High-quality Echinacea supplements will have clear and comprehensive labeling that includes the species of Echinacea used (e.g., Echinacea purpurea, Echinacea angustifolia), the part of the plant utilized (e.g., root, aerial parts), the concentration of active ingredients, dosage instructions, and any other ingredients or fillers. Transparency in labeling helps consumers make informed choices and avoid potential allergens or unwanted additives.
  5. Forms and Preparations: Echinacea is available in various forms, including capsules, tablets, tinctures, liquid extracts, and teas. The best form for you may depend on your preferences and needs. Liquid extracts and tinctures are often considered more potent and may be absorbed more quickly by the body. Capsules and tablets offer convenience and standardized dosing. Ensure that the form you choose is from a reliable source that adheres to high-quality standards.
  6. Organic and Sustainably Sourced: If possible, choose Echinacea products that are certified organic and sustainably sourced. Organic certification ensures that the plants were grown without the use of synthetic pesticides or fertilizers, which can contribute to a cleaner, healthier product. Sustainable sourcing practices help protect the environment and ensure the long-term availability of Echinacea.
  7. Consumer Reviews and Recommendations: Reading reviews and recommendations from other consumers can provide insights into the effectiveness and reliability of specific Echinacea products. Look for products with consistently positive feedback and high ratings from users who have similar health goals or conditions.

In summary, the best sources of Echinacea are reputable brands that offer standardized extracts, undergo third-party testing, provide clear labeling, and adhere to high-quality manufacturing practices. Choosing organic and sustainably sourced products can further enhance the quality and ethical considerations of your purchase. Always consult with a healthcare provider to determine the most suitable form and dosage for your individual needs.

Back to table of contents


What forms does Echinacea come in?

Echinacea is available in several different forms, each catering to various preferences and needs. The choice of form can influence the ease of use, absorption rate, and overall effectiveness of the supplement. Here are the most common forms of Echinacea:

  1. Capsules and Tablets: Capsules and tablets are among the most popular forms of Echinacea supplements. They provide a convenient and standardized way to consume Echinacea, ensuring consistent dosing. Capsules often contain powdered Echinacea, while tablets might include compressed extracts of the herb. This form is ideal for people who prefer a no-fuss, easy-to-swallow option.
  2. Liquid Extracts and Tinctures: Liquid extracts and tinctures are concentrated forms of Echinacea, typically made by soaking the herb in alcohol or glycerin to extract its active compounds. These forms are highly potent and offer faster absorption compared to capsules and tablets. Liquid extracts and tinctures are often administered using a dropper, allowing for precise dosing. They can be taken directly or mixed into water or juice. This form is particularly useful for individuals who need quick relief from symptoms or who have difficulty swallowing pills.
  3. Teas and Infusions: Echinacea teas and infusions are made by steeping the dried leaves, flowers, or roots of the plant in hot water. This form provides a soothing and enjoyable way to consume Echinacea, particularly during cold and flu season. Echinacea tea can be found in pre-packaged tea bags or as loose-leaf herbs. While teas may be less concentrated than other forms, they can still offer beneficial effects and are often combined with other herbs like elderberry or ginger for added immune support.
  4. Powders: Echinacea powders are made from dried and ground parts of the plant. These powders can be mixed into smoothies, juices, or other beverages, providing a versatile way to incorporate Echinacea into your diet. Powders offer flexibility in dosing and can be easily adjusted to meet individual needs. However, they may have a strong taste that some people find off-putting.
  5. Topical Preparations: Echinacea is also available in topical forms, such as creams, ointments, and salves. These preparations are typically used for their anti-inflammatory and wound-healing properties. Topical Echinacea can be applied directly to the skin to help with conditions like minor cuts, burns, insect bites, and skin infections. While not as commonly used as oral forms, topical Echinacea can be a valuable addition to a natural first aid kit.
  6. Chewables and Gummies: For those who prefer a more palatable form, Echinacea is available in chewable tablets and gummies. These options are particularly popular among children and individuals who dislike swallowing pills. Chewables and gummies often come in pleasant flavors and provide a tasty way to get the benefits of Echinacea. However, they may contain added sugars or other ingredients, so it's important to read the label carefully.

In summary, Echinacea comes in various forms, including capsules, tablets, liquid extracts, tinctures, teas, powders, topical preparations, and chewables or gummies. The best form for you will depend on your personal preferences, lifestyle, and specific health needs. Each form has its advantages, so consider your options and consult with a healthcare provider to determine which form and dosage are most appropriate for your situation.

Back to table of contents


Which sub-compounds of Echinacea, if any, are critical to the efficacy of Echinacea?

Echinacea's therapeutic effects are attributed to a variety of bioactive compounds found within the plant. These compounds work synergistically to enhance immune function, reduce inflammation, and provide antioxidant benefits. Here are some of the key sub-compounds that are critical to the efficacy of Echinacea:

  1. Alkamides: Alkamides are one of the most important groups of compounds in Echinacea, particularly in Echinacea purpurea and Echinacea angustifolia. These lipophilic molecules are known for their immune-modulating properties. Alkamides can interact with cannabinoid receptors (CB1 and CB2) in the immune system, potentially influencing immune cell function and inflammatory responses. Studies have shown that alkamides can stimulate phagocytosis, the process by which immune cells engulf and destroy pathogens, and enhance the activity of natural killer (NK) cells.
  2. Polysaccharides: Polysaccharides are complex carbohydrates found in Echinacea that have immunostimulatory effects. They can activate macrophages, a type of white blood cell that plays a crucial role in the immune response. By enhancing macrophage activity, polysaccharides help the body to more effectively identify and eliminate pathogens. Additionally, polysaccharides can stimulate the production of cytokines, signaling molecules that mediate and regulate immunity and inflammation.
  3. Caffeic Acid Derivatives: Caffeic acid derivatives, including cichoric acid and echinacoside, are phenolic compounds that contribute to Echinacea's antioxidant and immune-boosting properties. Cichoric acid, in particular, has been shown to enhance phagocytosis and stimulate the production of interferon, a protein that plays a key role in the defense against viral infections. Echinacoside exhibits antimicrobial and antioxidant activities, helping to protect cells from oxidative stress and support overall immune function.
  4. Flavonoids: Flavonoids are a diverse group of phytonutrients with potent antioxidant properties. In Echinacea, flavonoids like quercetin and kaempferol contribute to the plant's ability to scavenge free radicals and reduce oxidative stress. These compounds also have anti-inflammatory effects, which can help alleviate symptoms associated with infections and support the body's healing processes.
  5. Essential Oils: Echinacea contains essential oils that contribute to its antimicrobial and anti-inflammatory properties. These oils, which include compounds such as humulene and caryophyllene, can inhibit the growth of certain bacteria and fungi. Essential oils in Echinacea may also enhance the overall bioavailability of other active compounds, increasing the plant's therapeutic efficacy.
  6. Glycoproteins: Glycoproteins are proteins with carbohydrate chains attached, and they play a role in Echinacea's immune-enhancing effects. These compounds can stimulate immune cells and promote the production of cytokines, thereby supporting the body's defense mechanisms against pathogens.

In summary, the efficacy of Echinacea is largely due to the combined action of its bioactive compounds, including alkamides, polysaccharides, caffeic acid derivatives, flavonoids, essential oils, and glycoproteins. Each of these compounds contributes to the plant's immune-boosting, anti-inflammatory, and antioxidant properties, making Echinacea a valuable herbal supplement for supporting overall health. Understanding the presence and concentration of these sub-compounds in different Echinacea products can help consumers choose the most effective formulations for their needs.

Back to table of contents


What is Echinacea also known as?

Echinacea, a popular herbal remedy, is known by several names and can be found under various forms and preparations. Here are some of the common names, abbreviations, misspellings, and related terms associated with Echinacea:

Common Names:

  1. Coneflower: Echinacea species are commonly referred to as coneflowers due to their distinctive flower shape.
  2. Purple Coneflower: This name specifically refers to Echinacea purpurea, known for its purple petals.
  3. Black Sampson: An older common name, particularly for Echinacea angustifolia.

Abbreviations:

  1. ECH: A common abbreviation used in scientific literature and by some manufacturers.
  2. E. purpurea: Abbreviation for Echinacea purpurea.
  3. E. angustifolia: Abbreviation for Echinacea angustifolia.
  4. E. pallida: Abbreviation for Echinacea pallida.

Common Misspellings:

  1. Echinea
  2. Echinecea
  3. Echinicaea
  4. Echanacea

Chemical Compounds and Ingredients:

  1. Alkamides: These are lipid-based compounds found in Echinacea that contribute to its immune-modulating effects.
  2. Cichoric Acid: A caffeic acid derivative with antioxidant properties, commonly found in Echinacea.
  3. Echinacoside: Another caffeic acid derivative with antimicrobial and antioxidant activities.
  4. Polysaccharides: Complex carbohydrates that enhance immune function.
  5. Flavonoids: Phytonutrients with antioxidant and anti-inflammatory properties, such as quercetin and kaempferol.
  6. Essential Oils: These include compounds like humulene and caryophyllene, which have antimicrobial and anti-inflammatory effects.
  7. Glycoproteins: Proteins with attached carbohydrate chains that support immune function.

Latin Names:

  1. Echinacea purpurea: The most commonly used species in supplements and herbal remedies.
  2. Echinacea angustifolia: Known for its narrower leaves and is also used medicinally.
  3. Echinacea pallida: Another species used less frequently but still valued for its medicinal properties.

Herbal Preparations:

  1. Echinaforce: A popular commercial preparation of Echinacea purpurea.
  2. Echinilin: A proprietary extract standardized to contain specific active compounds.
  3. EchinaGuard: Another standardized Echinacea preparation used in various studies.
  1. Immunostimulant: A term often associated with Echinacea due to its ability to boost the immune system.
  2. Herbal Supplement: Echinacea is commonly categorized as a dietary supplement.
  3. Phytotherapy: The use of plant extracts for medicinal purposes, under which Echinacea falls.

In summary, Echinacea is known by various names, including coneflower and purple coneflower, and has several common misspellings such as "Echinea" and "Echinecea." Important compounds in Echinacea include alkamides, cichoric acid, echinacoside, polysaccharides, flavonoids, essential oils, and glycoproteins. Recognizing these terms can help consumers and practitioners identify high-quality Echinacea products and understand their potential benefits.

Back to table of contents


What is important to look for on the label of a Echinacea supplement to ensure product quality?

When selecting an Echinacea supplement, it’s crucial to carefully examine the label to ensure you are getting a high-quality product. Here are key factors to look for on the label:

  1. Species and Plant Parts Used:
    • Species Identification: The label should clearly state which species of Echinacea is used, such as Echinacea purpurea, Echinacea angustifolia, or Echinacea pallida. Different species have varying concentrations of active compounds and may offer different benefits.
    • Plant Parts: The label should specify which parts of the Echinacea plant are used, such as the roots, aerial parts (leaves, stems, and flowers), or a combination. Different parts of the plant contain different active constituents.
  2. Standardization of Active Compounds:
    • Active Ingredients: Look for products that are standardized to contain specific amounts of key active compounds, such as alkamides, cichoric acid, and polysaccharides. Standardization ensures consistency and potency in each dose.
    • Concentration: The concentration of active compounds should be clearly listed, usually as a percentage or specific milligram amount per serving.
  3. Dosage and Serving Size:
    • Recommended Dosage: The label should provide clear instructions on the recommended dosage and serving size, including how often to take the supplement.
    • Total Quantity: The total number of servings or capsules/tablets per container should be indicated, allowing you to understand how long the product will last at the recommended dosage.
  4. Third-Party Testing and Certifications:
    • Third-Party Verification: Look for evidence of third-party testing or certifications from reputable organizations such as NSF International, US Pharmacopeia (USP), or ConsumerLab. These certifications verify the product’s purity, potency, and safety.
    • Quality Seals: Certifications like GMP (Good Manufacturing Practices) compliance indicate that the product has been manufactured according to high-quality standards.
  5. Additional Ingredients:
    • Inactive Ingredients: Check the list of inactive ingredients for potential allergens, fillers, binders, or artificial additives. A high-quality product will have minimal unnecessary additives.
    • Other Herbal Ingredients: If the product contains additional herbal ingredients, these should be clearly listed along with their respective amounts.
  6. Expiration Date and Storage Instructions:
    • Expiration Date: Ensure the product has a clear expiration date to guarantee freshness and potency.
    • Storage Instructions: Proper storage instructions should be provided to maintain the efficacy of the supplement, such as keeping it in a cool, dry place.
  7. Manufacturer Information:
    • Contact Information: The label should include the name and contact information of the manufacturer or distributor, allowing you to reach out with any questions or concerns.
    • Country of Origin: Information about where the Echinacea was grown and where the product was manufactured can provide additional insights into quality control practices.
  8. Usage Warnings and Precautions:
    • Usage Instructions: Detailed instructions on how and when to take the supplement.
    • Warnings: Any warnings or precautions, such as potential allergic reactions or contraindications with certain medications, should be clearly stated.

In summary, when evaluating an Echinacea supplement, look for clear identification of species and plant parts used, standardization of active compounds, recommended dosage, third-party testing and certifications, minimal additional ingredients, expiration date, manufacturer information, and any relevant usage warnings. These factors will help you choose a high-quality Echinacea product that is both safe and effective.

Back to table of contents


Disclaimer & References

The information provided on this website, including any text, images, or other material contained within, is for informational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. This page was created by the SuppCo editiorial team, with AI summarization tools, including data from but not limited to following studies:

  1. R. Turner (2002). Echinacea for the Common Cold: Can Alternative Medicine Be Evidence-Based Medicine?. Annals of Internal Medicine, 137, 1001-1002. Link: 10.7326/0003-4819-137-12-200212170-00015
  2. B. Barrett, Roger L. Brown, K. Locken, R. Maberry, J. Bobula, D. D'alessio (2002). Treatment of the Common Cold with Unrefined Echinacea. Annals of Internal Medicine, 137, 939-946. Link: 10.7326/0003-4819-137-12-200212170-00006
  3. V. Goel, R. Lovlin, Chuck Chang, Jan V Slama, Richard E. Barton, R. Gahler, R. Bauer, L. Goonewardene, T. Basu (2005). A proprietary extract from the echinacea plant (Echinacea purpurea) enhances systemic immune response during a common cold. Phytotherapy Research, 19, . Link: 10.1002/ptr.1733
  4. B. Barrett, Roger L. Brown, D. Rakel, M. Mundt, K. Bone, S. Barlow, T. Ewers (2010). Echinacea for Treating the Common Cold. Annals of Internal Medicine, 153, 769 - 777. Link: 10.7326/0003-4819-153-12-201012210-00003
  5. Sachin A Shah, S. Sander, C. White, M. Rinaldi, C. Coleman (2007). Evaluation of echinacea for the prevention and treatment of the common cold: a meta-analysis. The Lancet. Infectious Diseases, 7, 473 - 480. Link: 10.1016/S1473-3099(07)70160-3
  6. Joel T. Giles, Cuthbert T. Palat, Su-Hui Chien, Z. G. Chang, D. T. Kennedy (2000). Evaluation of Echinacea for Treatment of the Common Cold. Pharmacotherapy, 20, 690 - 697. Link: 10.1592/phco.20.7.690.35173
  7. R. M. Brinkeborn, D. Shah, F. H. Degenring (1999). Echinaforce and other Echinacea fresh plant preparations in the treatment of the common cold. A randomized, placebo controlled, double-blind clinical trial.. Phytomedicine : international journal of phytotherapy and phytopharmacology, 6 1,
    1-6 . Link: 10.1016/S0944-7113(99)80027-0
  8. M. Karsch-Völk, B. Barrett, D. Kiefer, R. Bauer, K. Ardjomand-Woelkart, K. Linde (2014). Echinacea for preventing and treating the common cold.. The Cochrane database of systematic reviews, 2,
    CD000530 . Link: 10.1002/14651858.CD000530.pub3
  9. (2002). Treatment of Colds with a Capsule Form of the Herb Echinacea. Annals of Internal Medicine, 137, I-18. Link: 10.7326/0003-4819-137-12-200212170-00001
  10. V. Goel, Ray Lovlin, Richard E. Barton, M. R. Lyon, R. Bauer, T. D. G. Lee, T. K. Basu (2004). Efficacy of a standardized echinacea preparation (EchinilinTM) for the treatment of the common cold: a randomized, double‐blind, placebo‐controlled trial. Journal of Clinical Pharmacy and Therapeutics, 29, . Link: 10.1111/j.1365-2710.2003.00542.x
  11. Sholto David, R. Cunningham (2019). Echinacea for the prevention and treatment of upper respiratory tract infections: A systematic review and meta-analysis.. Complementary therapies in medicine, 44,
    18-26 . Link: 10.1016/J.CTIM.2019.03.011
  12. J. O'Neil, S. Hughes, A. Lourie, J. Zweifler (2008). Effects of echinacea on the frequency of upper respiratory tract symptoms: a randomized, double-blind, placebo-controlled trial. Annals of Allergy, Asthma & Immunology, 100, 384 - 388. Link: 10.1016/S1081-1206(10)60603-5
  13. D. Melchart, E. Walther, K. Linde, R. Brandmaier, C. Lersch (1998). Echinacea root extracts for the prevention of upper respiratory tract infections: a double-blind, placebo-controlled randomized trial.. Archives of family medicine, 7 6,
    541-5 . Link: 10.1001/ARCHFAMI.7.6.541
  14. W. Weber, James A. Taylor, A. Stoep, N. Weiss, L. Standish, C. Calabrese (2005). Echinacea purpurea for prevention of upper respiratory tract infections in children.. Journal of alternative and complementary medicine, 11 6,
    1021-6 . Link: 10.1089/ACM.2005.11.1021
  15. S. Sharma, M. Anderson, S. Schoop, J. Hudson (2010). Bactericidal and anti-inflammatory properties of a standardized Echinacea extract (Echinaforce): dual actions against respiratory bacteria.. Phytomedicine : international journal of phytotherapy and phytopharmacology, 17 8-9,
    563-8 . Link: 10.1016/j.phymed.2009.10.022
  16. Riska Fajar Fatony, D. Tamtomo, Hanung Prasetya (2020). The Effect Echinacea Purpurea Herbs in Reducing Symptoms of Upper Respiratory Infection: A Meta-Analysis. {"title"=>"", "scimago_quartile"=>nil}, , . Link: 10.26911/THE7THICPH.05.58
  17. B. Barrett, Monica Vohmann, C. Calabrese (1999). Echinacea for upper respiratory infection.. The Journal of family practice, 48 8,
    628-35 . Link:
  18. A. Schapowal, P. Klein, S. Johnston (2015). Echinacea Reduces the Risk of Recurrent Respiratory Tract Infections and Complications: A Meta-Analysis of Randomized Controlled Trials. Advances in Therapy, 32, 187-200. Link: 10.1007/s12325-015-0194-4
  19. H. Hall, M. Fahlman, H. Engels (2007). Echinacea purpurea and mucosal immunity.. International journal of sports medicine, 28 9,
    792-7 . Link: 10.1055/S-2007-964895
  20. Jamal Islam, R. Carter (2005). Use of Echinacea in Upper Respiratory Tract Infection. Southern Medical Journal, 98, 311-318. Link: 10.1097/01.SMJ.0000154783.93532.78

Back to table of contents

These statements have not been evaluated by the Food and Drug Administration. Any products and informational content displayed on this page are not intended to diagnose, treat, cure, or prevent any disease.