The Most Clinically Studied Products on SuppCo

The Most Clinically Studied Products on SuppCo

It is one thing to make a supplement. It is another to study it. At SuppCo, we reward products that go beyond formulation and invest in peer-reviewed clinical trials using the final, finished product. This is a cornerstone of our TrustScore system. Products that meet this bar are rare, and those with studies published in reputable journals are rarer still.

Here we are spotlighting the most stacked products in our database when it comes to clinical study quality. Each of the products below has a published human study and a TrustScore to match. If clinical validation matters to you, these are the brands to watch.

1. AG1: AG1 The Pouch (TrustScore 9.25)
   Study: "The effects of AG1® supplementation on the gut microbiome of healthy adults: a randomized, double-blind, placebo-controlled clinical trial" 

2. Fatty15: C15:0 Fatty Acid Supplement (TrustScore 9.63)
   Study: "Pentadecanoic Acid Supplementation in Young Adults with Overweight and Obesity: A Randomized Controlled Trial"

3. Timeline: Mitopure Urolithin A (TrustScore 10.00)
   Study: "Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized controlled trial in middle-aged adults"

4. TruNiagen: Tru Niagen 300mg (TrustScore 10.00)
   Study: "Safety and Metabolism of Long-term Administration of NIAGEN (Nicotinamide Riboside Chloride) in a Randomized, Double-Blind, Placebo-controlled Clinical Trial of Healthy Overweight Adults"

5. Big Bold Health: HTB Rejuvenate (TrustScore 9.69)
   Study: “The impact of a polyphenol-rich supplement on epigenetic and cellular markers of immune age: a pilot clinical study” 

6. Nutrafol: Women Hair Growth Nutraceutical (TrustScore 9.88)
   Study: “A Six-Month, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of a Nutraceutical Supplement for Promoting Hair Growth in Women With Self-Perceived Thinning Hair”

7. Elysium: Basis (TrustScore 9.75)
   Study: "Repeat dose NRPT (nicotinamide riboside and pterostilbene) increases NAD+ levels in humans safely and sustainably: a randomized, double-blind, placebo-controlled study"

8. Pendulum: Glucose Control (TrustScore 9.13)
   Study: "Improvements to postprandial glucose control in subjects with type 2 diabetes: a multicenter, double blind, randomized placebo-controlled trial of a novel probiotic formulation"

9. BODYBIO: Sodium Butyrate (TrustScore 9.25)
   Study: “Effects of short-chain fatty acid-butyrate supplementation on expression of circadian-clock genes, sleep quality, and inflammation in patients with active ulcerative colitis: a double-blind randomized controlled trial”

10. Centrum: Men Multivitamin (TrustScore 6.31)
    Study: “Comparison of the effects of coenzyme Q10 and Centrum multivitamins on semen parameters, oxidative stress markers, and sperm DNA fragmentation in infertile men with idiopathic oligoasthenospermia”

These brands represent the gold standard of evidence in the supplement space. While formulations and sourcing matter, it is clinical validation that often sets products apart. 

Each of these companies has invested in research not just to promote their products, but to better understand how they work. At SuppCo, we believe this level of rigor is worth highlighting.